Is Amoxicillin Safe for Pregnant Women? A Complete Guide

Pregnancy is a beautiful yet sometimes challenging time, especially when you’re not feeling your best. Symptoms like a stuffy nose, fatigue, or body aches can often feel like signs of something more serious. In some cases, a bacterial infection may be the culprit, and your doctor may prescribe antibiotics like amoxicillin to treat it.
But is amoxicillin safe during pregnancy? Will it harm your baby? Here, we provide expert insights to help you understand everything you need to know about using amoxicillin while pregnant.
Is Amoxicillin Safe for Pregnant Women?

Generally speaking, amoxicillin is considered safe for pregnant women—unless they are allergic to the drug—and is unlikely to harm the fetus. The FDA classifies amoxicillin as a “Category B” pregnancy drug. This means that while animal studies have shown no harm to the fetus, there is no high-quality human research available to confirm its safety during pregnancy.
If you have a bacterial infection while pregnant, your doctor may prescribe amoxicillin to treat it. “Amoxicillin is one of the most commonly prescribed antibiotics to treat ear infections, urinary tract infections, bacterial infections (such as sinus infections), and skin infections,” says Ersilia Pompilio RN, MSN, PNP.
Though taking antibiotics during pregnancy might not be ideal, Dr. Staci L. McHale, a leading obstetrician at New Beginnings Obstetrics & Gynecology in Las Vegas, emphasizes that the risks are minimal. “Amoxicillin is one of the safest antibiotics to use during pregnancy and breastfeeding. Numerous studies show that it poses very little risk to an unborn baby, and if necessary, it can be safely used to treat infections in pregnant women.”
Can Amoxicillin Affect Your Baby During Pregnancy?
Taking medications—especially prescription drugs—during pregnancy can understandably cause concern. However, according to Pompilio, the risk to the baby is extremely low. “Amoxicillin is considered a low-risk drug that can be safely used during any trimester of pregnancy. There is no evidence to suggest that amoxicillin causes harm to an unborn baby when taken by the mother.”
If you’re ever unsure whether the medication you’re taking could affect your baby, whether it’s a prescription or over-the-counter drug, it’s always best to consult with your obstetrician or primary care doctor to ensure it’s safe.
What to Do if You Experience Side Effects
While amoxicillin is generally safe, some women may experience side effects such as severe vomiting or diarrhea. If this happens, it’s essential to contact your doctor. They may decide to stop the medication or switch you to a different antibiotic. Additionally, if you experience serious side effects like allergic reactions, seizures, unusual bleeding, or yellowing of the skin or eyes, seek medical attention immediately.
Can You Get Pregnant While Taking Amoxicillin?
Yes, amoxicillin does not affect a woman’s fertility or her ability to get pregnant. Pompilio explains, “Various studies suggest that certain antibiotics may interfere with hormonal medications or birth control, but there is no evidence that amoxicillin interferes with the fertility process, conception, or menstrual cycle.”
However, if you’re trying to conceive, your male partner should avoid certain antibiotics that can affect sperm and fertility. “Penicillin, tetracycline, and erythromycin have been shown to negatively impact male fertility and sperm quality,” says Pompilio. If this applies to your situation, your partner may want to discuss alternatives with their doctor.
The Bottom Line: Talk to Your Doctor
If you’re pregnant and prescribed amoxicillin, rest assured that it is generally safe and poses minimal risks to both you and your baby. However, it’s important to communicate with your doctor about which stage of pregnancy you’re in so they can provide the best treatment options without any potential harm to your baby. Always consult your healthcare provider if you’re unsure about any medication you’re taking during pregnancy. Your doctor can offer personalized advice to ensure both your health and your baby’s well-being.
